Association of primary knee osteoarthritis with DVWA SNP in a group of Egyptian population: a case–control study

Egyptian Journal of Medical Human Genetics

Table 5 Relation between DVWA rs11718863 single nucleotide polymorphism with WOMAC and HAQ scores results in patient group

WOMAC and AQ scores results	DVWA rs11718863 SNP genotype				Test of significance	p
	AA (n = 35)		AT + TT (n = 15)
	No.	%	No.	%
WOMAC total
Mean ± SD	50.20 ± 12.42		52.20 ± 8.58		t = 0.402	0.689
WOMAC interpretation
Mild	3	8.6	0	0.0	χ² = 1.893	0.595
Moderate	9	25.7	4	26.7
Severe	22	62.9	11	73.3
Extreme	1	2.9	0	0.0
HAQ score
Mean ± SD	1.18 ± 0.55		0.98 ± 0.42		t = 1.228	0.225
HAQ interpretation
Mild	19	54.3	9	60.0	χ² = 0.918	0.632
Moderate	14	40.0	6	40.0
Severe	2	5.7	0	0.0

DVWA double Von Willebrand factor domain A, HAQ Health Assessment Questionnaire, P P value for comparison between AA and AT + TT, SD standard deviation, SNP single nucleotide polymorphism, t value of Student’s t test, χ² value of chi-square test, WOMAC Western Ontario and McMaster Universities Osteoarthritis Index, % percentage of patients
*Statistically significant at P ≤ 0.05