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Table 1 Summary of genetic diversity of P. falciparum isolates in Nigeria

From: Genetic diversity of Plasmodium falciparum isolates in Nigeria. A review

  

Allelic Families

 
  

msp 1

msp 2

 

Multiplicity of Infection

   

State

Place of Research

K1

MAD20

RO33

FC27

3D7

Sample size

MSP-1

MSP-2 

Type of population

References

Kogi (North Central)

Idah

70%

20%

40%

40%

20%

80

1.05

2.13

Riverine communities

[30]

 

Ibaji

40%

10%

20%

30%

20%

 

1.30

2

  

Kwara (North Central)

Okelele

56.25%

41.67%

47.92%

43.75%

27.08%

50

1.7

1.8

Rural community

[31]

Nassarawa (North Central)

Lafia

NA

NA

NA

60.5%

39.5%

93

2.31

 

Children in a similar microenvironment

[24]

Nassarawa (North Central)

Lafia

NA

NA

NA

45%

55%

116

-

1.3

Children (1-8yrs)

[18]

Nassarawa (North Central)

Lafia

NA

NA

NA

59%

38%

180

-

2.2

Asymptomatic group

[23]

  

NA

NA

NA

45%

51%

140

-

2.0

Uncomplicated malaria group

 

Niger (North Central)

Minna

46%

67%

11%

93%

24%

50

1.54

1.68

Infants and children (6 months-17 years)

[15]

Kaduna (North West)

Kaduna Metropolis

20%

60%

0%

25%

62.5%

30

NA

Symptomatic

 

[19]

  

0%

20%

0%

8.33%

4.17%

12

NA

Asymptomatic

  

Lagos (South West)

Ajeromi-Ifelodun General Hospital, Lagos

38%

17%

29%

33%

29%

24

1.05

1.07

Pregnant women

[34]

  

25%

25%

33%

29%

38%

24

1.15

1.25

Non-pregnant women

 

Lagos (South West)

Lekki

70%

50%

50%

94%

30%

50

1.39

1.76

Urban

[36]

 

Ikorodu

50%

50%

40%

70%

40%

50

1.50

1.14

Peri-urban area

 

Lagos (South West)

Lagos State Teaching Hospital

89.5%

31.6%

26.3%

NA

NA

19

1.4

Sickle cell anaemia patients (rural)

[26]

  

72.2%

33.3%

5.6%

NA

NA

18

1.5

Sickle cell anaemia patients (urban)

 

Lagos (South West)

Lekki

NA

NA

NA

31.0%

19.7%

195

1.54

Patients from 3 different hospitals

[40]

Ogun (South West)

Ijebu

20.6%

22.5%

30%

23.2%

21.1%

20

1.1

1.2

Ogun State General Hospital

[35]

 

Yewa

45.6%

52.5%

40%

32.1%

50%

43

    
 

Egba

22.1%

17.5%

20%

32.1%

15.8%

25

    
 

Remo

11.8%

7.5%

10%

12.5%

13.2%

12

    

Oyo (South West)

Ibadan

94%

75%

68%

NA

NA

53

-

-

AM

[41]

  

79%

54%

61%

NA

NA

101

-

-

UM

 
  

74%

49%

57%

NA

NA

69

-

-

SM

 

Oyo (South west)

Idi-Ayunre

2.6%

3.3%

7.3%

3D7 + FC27 68.3%

43.20%

309

2.8

Rural community

[28]

 

St. Mary Healthcare

10.0%

10.0%

10.0%

15.00%

15.00%

 

2.6

Urban community

 

Oyo (South West)

Igbo-Ora

26%

17%

57%

NA

NA

143

1.7

Individuals with submicroscopic infection

[33]

Oyo (South West)

Ibadan

NA

NA

NA

35%*

45%*

75*

-

2.8

UM in two populations (A and B)

[25]

     

50%

78%

115

 

2.1

  
  

NA

NA

NA

11%*

28%*

48*

-

3.4

CM in two populations (A and B)

 
     

52%

56%

55

 

1.3

  
  

NA

NA

NA

40%*

13%*

41*

-

1.9

SMA in two populations (A and B)

 
     

57%

58%

55

  

1.5

 

Oyo (South West)

Ibadan

79%

32%

38%

85.1%

85.1%

47

2.5

4.9

Children with failed chloroquine treatment

[32]

Osun (South West)

Osogbo

NA

NA

NA

62.3%

68.1%

101

1.6

Ages 0–4

[42]

     

76.2%

62%

 

1.8

Ages 4–8

 
     

73.0%

27.3%

 

1.3

Ages 9–12

Â