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Egyptian Journal of Medical Human Genetics

Table 4 Distribution of genotype and allele frequencies of IL-10 (rs1800896 and rs1800872) gene polymorphisms in mild and severe COVID-19 patients

From: Implication of single nucleotide polymorphisms in Interleukin-10 gene (rs1800896 and rs1800872) with severity of COVID-19

 

Mild (n = 85)

Severe (n = 75)

Statistical analysis

Genotypes/alleles

N

%

N

%

Chi-sq

p value

OR

95% CI

IL-10 (rs1800896)

AA

45

52.9

49

65.3

2.52

0.112

1.68

(0.88–3.17)

AG

38

44.7

23

30.7

3.33

0.068

0.55

(0.29–1.05)

GG

2

2.4

3

4.0

0.36

0.550

1.73

(0.28–10.64)

G

42

24.7

29

19.3

1.33

0.248

0.73

(0.43–1.25)

A

128

75.3

121

80.7

1.33

0.248

1.37

(0.80–2.34)

IL-10 (rs1800872)

CC

38

44.7

24

32.0

2.71

0.010

0.58

(0.30–1.11)

CA

39

45.9

41

54.7

1.23

0.267

1.42

(0.76–2.65)

AA

8

9.4

10

13.3

0.61

0.433

1.48

(0.55–3.97)

A

55

32.4

61

40.7

2.38

0.123

1.43

(0.91–2.26)

C

115

67.6

89

59.3

2.38

0.123

0.70

(0.44–1.10)

  1. Statistically signficant values are shown in bold
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