Egyptian Journal of Medical Human Genetics

Table 3 Genotype and allele frequencies of IL 6 and IL 8 polymorphisms in control and patient groups (*** signifies p < 0.0001 and values are significant)

From: Association of Interleukin 6 and Interleukin 8 genes polymorphisms with house dust mite-induced nasal-bronchial allergy in a sample of Indian patients

SNPs (position)	Genotype and allele	Patients	Controls	OR	Chi-square value	P value
		(N = 372)	(N = 110)	(95% CI)
IL 6 rs1800796 (− 572)	Genotype
	GG	102 (27.42)	50 (45.45)
	GC	198 (53.22)	52 (47.27)		16.78	< 0.0001***
	CC	72 (19.35)	8 (7.27)
	Allele
	G	402 (54.03)	152 (69.1)	0.5259 (0.3817–0.7244)
	C	342 (45.97)	68 (30.91)			< 0.0001***
IL 6 rs1800797 (− 597)	Genotype
	GG	259 (69.62)	76 (69.1)
	GA	102 (27.42)	34 (30.9)		0.1876	0.6649
	AA	11 (2.95)	0 (0.0)
	Allele
	G	620 (83.33)	186 (84.54)	0.9140 (0.6–1.4)		0.7559
	A	124 (16.67)	34 (15.45)
IL 8 rs4073 (− 251)	Genotype
	AA	99 (26.61)	46 (41.82)
	AT	195 (52.42)	55 (50)		14.25	0.0002***
	TT	78 (20.96)	9 (8.18)
	Allele
	A	393 (52.82)	147 (66.82)	0.5560(0.4056–0.7623)		0.0003***
	T	351 (47.17)	73 (33.18)
IL 8 rs2227306 (+ 781)	Genotype
	CC	201 (54.03)	56 (50.91)		0.0372	0.847
	CT	155 (41.67)	54 (49.1)
	TT	16 (9.3)	0 (0.0)
	Allele
	C	557 (74.86)	166 (75.45)	0.9689(0.6835–1.374)		0.9294
	T	187 (25.13)	54 (24.54)

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