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Table 11 Inter-molecular H- bonding and Clash Analysis of Wild and mutant structure of modeled PLCε1 according to chimera

From: Mutational analysis of phospholipase C epsilon 1 gene in Egyptian children with steroid-resistant nephrotic syndrome

Position/analysis

1230

1393

Wild

Mutant

Wild

Mutant

H-Bonding analysis

1 H-bond with Lys 1234 with distance = 3.241 Å

1 H-bond with Lys 1234 with distance = 3.241 Å

2 H- bonds found with ASN 1390 distance 2.671 and 3.339 Å

1 H-bond found with ASN 1390 3.339 and the another H- bond lost

Inter-molecular Clashes analysis

1 clash found with SER 1229 with distance2.484 Å

20 clashes found with ARG1276, ARG1228, and LYS1231

No clahes found

20 clashes found with LEU 1840 and LYS1392