Fig. 1
From: TMPRSS6 gene polymorphisms associated with iron deficiency anaemia among global population
Structure of TMPRSS6 gene on chromosome 22 and the encoded MT-2 protein domain. The upper panel of the picture shows the TMPRSS6 genomic organisation, with black and white boxes representing coding and non-coding areas, respectively. In the lower panel is the encoded protein. Dashed lines indicate exon encoding boundaries for each of the MT-2 protein structural domains, which include transmembrane (TM), one SEA, two CUBs, three LDL-receptor class A (L), activation (blue box), and trypsin-like serine protease domains (red box)