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Table 2 Genotype frequencies for the SNPs in the control and CVD groups (360 samples) in different genetic models

From: Association of the ANGPTL3 gene polymorphisms and haplotypes with cardiovascular diseases in Birjand longitudinal aging study (BLAS)

Genotype/Allele

CVD

CVA

AMI

CHD

Yes (n = 128)

No (n = 231)

P

Yes (n = 25)

No (n = 322)

P

Yes (n = 78)

No (n = 277)

P

Yes (n = 39)

No (n = 320)

P

rs1748195

 CC

50 (39.1)

122 (52.8)

0.008

11 (44.0)

160 (48.0)

0.815

28 (35.9)

142 (51.3)

0.030

18 (46.2)

154 (48.1)

0.370

 CG

49 (38.3)

82 (35.5)

 

9 (36.0)

122 (36.6)

 

32 (41.0)

97 (35.0)

 

12 (30.8)

119 (37.2)

 

 GG

29 (22.7)

27 (11.7)

 

5 (20.0)

51 (15.3)

 

18 (23.1)

38 (13.7)

 

9 (23.1)

47 (14.7)

 

 C

149 (58.2)

326 (70.6)

0.001

31 (62.0)

442 (66.4)

 

88 (56.4)

381 (68.8)

0.004

48 (61.5)

427 (66.7)

0.361

 G

107 (41.8)

136 (29.4)

 

19 (38.0)

224 (33.6)

0.529

68 (43.6)

173 (31.2)

 

30 (38.5)

213 (33.3)

 

rs10789117

 AA

61 (47.7)

109 (47.2)

0.083

12 (48.0)

157 (47.1)

 

33 (42.3)

134 (48.4)

0.099

19 (48.7)

151 (47.2)

0.984

 AC

44 (34.4)

98 (42.4)

 

5 (20.0)

137 (41.1)

0.006

29 (37.2)

112 (40.4)

 

15 (38.5)

127 (39.7)

 

 CC

23 (18.0)

24 (10.4)

 

8 (32.0)

39 (11.7)

 

16 (20.5)

31 (11.2)

 

5 (12.8)

42 (13.1)

 

 A

166 (64.8)

316 (68.4)

0.331

29 (58.0)

451 (67.7)

 

95 (60.9)

380 (68.6)

0.071

53 (67.9)

429 (67.0)

0.871

 C

90(35.2)

146 (31.6)

 

21 (42.0)

215 (32.3)

0.159

61 (39.1)

174 (31.4)

 

25 (32.1)

211 (33.0)

 

rs11207997

 CC

28 (21.9)

65 (28.1)

0.021

5(20.0)

88 (26.4)

 

20 (25.6)

71 (25.6)

 

9 (23.1)

84 (26.3)

 

 CT

91 (71.1)

162 (70.1)

 

19 (76.0)

233 (70.0)

0.858

52 (66.7)

199 (71.8)

1.000

28 (71.8)

225 (70.3)

0.801

 TT

9 (7.0)

4 (1.7)

 

1 (4.0)

12 (3.6)

 

6 (7.7)

7 (2.5)

 

2 (5.1)

11 (3.4)

 

 C

147 (57.4)

292 (63.2)

0.128

29 (58.0)

409 (61.4)

0.633

92 (59.0)

341 (61.6)

 

46 (59.0)

393 (61.4)

 

 T

109 (42.6)

170 (36.8)

 

21 (42.0)

257 (38.6)

 

64 (41.0)

213 (38.4)

0.560

32 (41.0)

247 (38.6)

0.677

  1. CVD Cardiovascular disease, CVA Cerebrovascular accident, AMI Acute myocardial infarction, CHD Coronary heart disease