Table 3 Association of ANGPTL3 genotype and CVD risk in the studied population
Genotype/allele | Total N (%) | CVD N (%) | No CVD N (%) | Univariate | Multivariate* | ||
|---|---|---|---|---|---|---|---|
Odds ratio (95%CI) | P | Odds ratio (95%CI) | P | ||||
rs1748195 | |||||||
 CC | 172 (47.9) | 50 (39.1) | 122 (52.8) | Ref.1 | Ref.1 | Ref.1 | Ref.1 |
 CG | 131 (36.5) | 49 (38.3) | 82 (35.5) | 1.46 (0.90–2.36) | 0.126 | 1.58 (0.94–2.67) | 0.084 |
 GG | 56 (15.6) | 29 (22.7) | 27 (11.7) | 2.62 (1.41–4.87) | 0.002 | 2.43 (1.25–4.71) | 0.008 |
 C | 475 (66.2) | 149 (58.2) | 326 (70.6) | Ref.1 | Ref.1 | Ref.1 | Ref.1 |
 G | 243 (33.8) | 107 (41.8) | 136 (29.4) | 1.72 (1.25–2.37) | 0.001 | NA | NA |
rs10789117 | |||||||
 AA | 170 (47.4) | 61 (47.7) | 109 (47.2) | Ref.1 | Ref.1 | Ref.1 | Ref.1 |
 AC | 142 (39.6) | 44 (34.4) | 98 (42.4) | 0.80 (0.50–1.29) | 0.362 | 0.90 (0.55–1.49) | 0.695 |
 CC | 47 (13.1) | 23 (18.0) | 24 (10.4) | 1.71 (0.89–3.29) | 0.106 | 1.66 (0.81–3.40) | 0.163 |
 A | 482 (67.1) | 166 (64.8) | 316 (68.4) | Ref.1 | Ref.1 | Ref.1 | Ref.1 |
 C | 236 (32.9) | 90 (35.2) | 146 (31.6) | 1.17 (0.85–1.62) | 0.330 | NA | NA |
rs11207997 | |||||||
 CC | 93 (25.9) | 28 (21.9) | 65 (28.1) | Ref.1 | Ref.1 | Ref.1 | Ref.1 |
 CT | 253 (70.5) | 91 (71.1) | 162 (70.1) | 1.30 (0.78–2.17) | 0.310 | 1.45 (0.84–2.51) | 0.188 |
 TT | 13 (3.6) | 9 (7.0) | 4 (1.7) | 5.22 (1.48–18.38) | 0.010 | 4.80 (1.27–18.11) | 0.021 |
 C | 439 (61.1) | 147 (57.4) | 292 (63.2) | Ref.1 | Ref.1 | Ref.1 | Ref.1 |
 T | 279 (38.9) | 109 (42.6) | 170 (36.8) | 1.27 (0.93–1.74) | 0.128 | NA | NA |