Autophagy-related genes in Egyptian patients with Behçet's disease

Egyptian Journal of Medical Human Genetics

Table 4 Association of disease manifestation with relative mRNA expression of different studied autophagy genes

Genes	ATG5		ATG7		ATG12		mTOR		LC3b
Genes	F	P	F	P	F	P	F	P	F	P
Age	4.97	0.000	4.38	0.001	1.18	0.351	0.38	1.00	0.33	1.00
Male	1.67	0.212	2.72	0.112	0.05	0.821	1.24	0.281	0.00	0.961
Family history	1.22	0.281	3.02	0.102	1.30	0.273	0.01	0.912	0.11	0.743
Mouth ulcers	8.87	0.011	1.20	0.293	0.84	0.373	0.26	0.622	0.95	0.343
Genital ulcers	0.27	0.613	0.56	0.463	0.93	0.352	0.34	0.573	0.13	0.722
Erythema nodosum	1.27	0.271	6.08	0.021	0.00	0.972	0.06	0.811	1.06	0.321
Pustules	1.93	0.182	1.34	0.261	0.04	0.851	0.49	0.493	5.83	0.033
Arthralgia	0.47	0.501	0.55	0.472	1.04	0.321	0.04	0.843	0.77	0.391
Arthritis	0.39	0.543	0.71	0.412	1.44	0.242	1.00	0.331	0.01	0.942
GIT illness	0.01	0.922	0.23	0.643	0.70	0.412	0.28	0.602	1.04	0.322
Ocular problems	3.81	0.063	2.98	0.101	0.00	0.963	0.00	0.982	0.05	0.823
CNS complications	0.16	0.691	0.34	0.571	0.83	0.371	1.36	0.263	0.01	0.911
Major vascular lesion	1.36	0.263	4.99	0.043	1.59	0.221	1.00	0.333	0.03	0.862
Pulmonary diseases	0.28	0.602	0.94	0.342	0.85	0.373	0.75	0.402	0.03	0.871

F General linear model with stepwise elimination, P p value and p considered significant if p < 0.05