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Table 2 The Hardy–Weinberg equilibrium of HLA-DRB1 and -DQB1 loci in selected populations of South India

From: The HLA profile and genetic affinities of three primitive Tamil-speaking endogamous groups: Kallars of Thanjavur, Piramalai Kallar and Vanniyar

Kallars of Thanjavur

Piramalai Kallar

Vanniyar

Locus

Genotypes

Obs

Exp

X2

p-value

Obs

Exp

X2

p-value

Obs

Exp

X2

p-value

DRB1

Homozygote Reference

41

50.2

14.735

0.0001

27

34.9

14.821

0.0001

44

53.1

  

Heterozygote

70

51.5

53

37.2

75

56.7

12.975

0.0003

Homozygote

Variant

04

13.2

02

9.9

06

15.1

DQB1

Homozygote Reference

49

57.1

14.214

0.0001

33

39.9

13.839

0.0001

48

56.7

  

Heterozygote

62

45.7

47

33.2

71

53.6

12.902

0.0003

 

Homozygote Variant

01

9.1

ND

ND

04

12.7

  
  1. Obs. Observed, Exp. expected, ND not detected