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Egyptian Journal of Medical Human Genetics

Table 5 The comparison of hematological response between responder and resistant groups

From: Effects of ABCG2 C421A and ABCG2 G34A genetic polymorphisms on clinical outcome and response to imatinib mesylate, in Iranian chronic myeloid leukemia patients

Index

Responder*

Resistant**

Primary***

Secondary****

P

Primary

Secondary

P

WBC (× 103 cell/μL)

168.950 ± 345.076

704.900 ± 278.401

0.110

776.413 ± 661.808

775.800 ± 578.235

0.236

Plt (× 105/μL)

2.63250 ± 1.59091

2.69400 ± 1.29271

0.978

1.81066 ± 9.45490

1.89733 ± 9.79390

0.946

Hb (g/dL)

12.19 ± 2.22

12.25 ± 2.18

0.806

12.66 ± 1.40

12.62 ± 1.28

0.724

  1. *WBC < 10 × 109/L/ platelet < 450 × 109/L/ an absence of myelocytes, promyelocytes, or myeloblasts in peripheral blood
  2. **WBC and platelet counts have not returned to normal, there are immature cells seen in blood
  3. ***Before drug intake
  4. ****After drug intake
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