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Table 1 MTHFR genotype frequency distribution in cases and controls

From: Association of MTHFR C677T polymorphism with risk of preterm birth in Indian mothers: a case–control study

Polymorphism

Genotype/allele

Control (full-term mothers) (N = 100) n f (%)

Cases (preterm mothers) (N = 100) n f (%)

Chi-square and p value

OR (95% CI)

C677T

CC

56 (56%)

36 (36%)

1

 

CT

44 (44%)

61 (61%)

7.06**

2.16 (1.21–3.79)

 

TT

0

3 (3%)

4.45*

Infinity (1.28-Infinity)

 

C

156 (78%)

133 (66.5%)

1

 

T

44 (22%)

67 (33.5%)

6.60*

1.79(1.13–2.81)

  1. Statistical analysis is done by the chi-square test. n—number of genotypes, f—frequency, **p < 0.01; *p < 0.05