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Table 4 Correlation of CBMN-Cyt assay markers with MTHFR polymorphism in cases and controls

From: Association of MTHFR C677T polymorphism with risk of preterm birth in Indian mothers: a case–control study

CBMN-Cyt markers

Control (N = 100)

Cases (N = 100)

CC

CT

TT

CC

CT

TT

Micronucleus

4.48 ± 0.13

4.89 ± 0.19####

00####

5.17 ± 0.22**

5.90 ± 0.14 ****##

6.33 ± 0.33****##

Nuclear bridge

0.11 ± 0.04

0.20 ± 0.06 ns

00 ns

0.17 ± 0.06 ns

0.30 ± 0.06 ns; ns

0.67 ± 0.33 ns; ns

Nuclear bud

0.04 ± 0.03

0.11 ± 0.05 ns

00 ns

0.08 ± 0.05 ns

0.28 ± 0.06*; #

0.67 ± 0.33 ns; #

  1. Results are expressed as the mean value ± SEM. Data were analysed by unpaired t test and one-way ANOVA
  2. *Comparison between the group: Control vs Cases, CC vs CC, CT vs CT, TT vs TT: *p < 0.05; **p < 0.01; ****p < 0.0001; ns—non-significant
  3. #Comparison within each group
  4. Control: CC vs CT vs TT: ####p < 0.0001, ns—non-significant
  5. Cases: CC vs CT vs TT: #p < 0.05; ##p < 0.01; ns—non-significant