Table 3 Genotype and allele frequencies of FOXP3 rs3761548 and rs5902434 patients and control subjects in Iranian population
SNP | Model | Allele/genotype | Migraine (%) | Controls (%) | Odd ratio | p value |
|---|---|---|---|---|---|---|
rs3761548 | C | 70 (63.6%) | 137 (85.6%) | 1.40 (0.89- 1.12) | 0.00 | |
A | 40 (36.4%) | 23 (14.4%) | ||||
Dominant | C/C | 27 (49.1%) | 63 (78.8%) | 0.26 (0.12–0.55) | 0.00 | |
A/C-A/A | 28 (50.9%) | 17 (21.2%) | ||||
Recessive | C/C-A/C | 43 (78.2%) | 74 (92.5%) | 2.44 (0.20–1.83) | 0.01 | |
A/A | 12 (21.8%) | 6 (7.5%) | ||||
rs5902434 | ATT (A) | 66 (41.2%) | 45 (39.8%) | 0.94 (0.57–1.54) | 0.90 | |
Deletion (T) | 94 (58.8%) | 68 (60.2%) | ||||
Dominant | Deletion/Deletion | 16 (29.1%) | 17 (21.2%) | 1.52 (0.68–1.35) | 0.29 | |
Deletion/ATT-ATT/ATT | 39 (70.9%) | 63 (78.8%) | ||||
Recessive | Deletion/Deletion-Deletion/ATT | 55 (94.8%) | 77 (96.2%) | 1.40 (0.27–1.19) | 0.68 | |
ATT/ATT | 3 (5.5%) | 3 (3.8%) |