A case–control study of single-nucleotide variants in microRNA biogenesis genes (AGO1 and GEMIN4) in people with primary immune thrombocytopenia

Egyptian Journal of Medical Human Genetics

Table 2 Genotypes and age of onset and duration of disease

	Age at onset Mean ± SD (years)	p-value *	Duration of disease Mean ± SD (years)	p-value *
AGO1rs636832 A/G
AA	24.000 ± 8.775	0.301	0.374 ± 0.217	0.301
AG	25.864 ± 12.021		2.087 ± 3.412
GG	33.11 ± 15.496		2.581 ± 3.229
Recessive model
AA + AG	25.519 ± 11.362	0.022*	1.770 ± 3.142	0.264
GG	33.110 ± 15.496		2.581 ± 3.229
GEMIN4 rs2740348 G/C
GC	34.375 ± 18.5	0.513	1.334 ± 1.768	0.348
CC	30.772 ± 14.56		2.451 ± 3.297