Table 2 Clinical and pathological characterization of familial versus non-familial BC patients
Characteristic | Familial BC (N = 50) | Non-familial BC (N = 50) | P value |
|---|---|---|---|
Age [year] | |||
Range | 27–78 | 29–72 | 0.223a |
Mean ± SD | 51.98 ± 10.969 | 49.34 ± 11.994 | |
NA | 1 | 0 | |
Tumor size [cm] | |||
Mean ± SD | 2.8 ± 1.5 | 2.9 ± 1.71 | 0.813a |
Pathology | |||
Ductal Carcinoma In Situ | 10 (20%) | 7 (14%) | 0.769b |
Invasive Ductal Carcinoma | 33 (66%) | 34 (68%) | |
Invasive Lobular Carcinoma | 7 (14%) | 9 (18%) | |
Tumor grade | |||
G1 | 5 (10%) | 6 (12%) | 0.364b |
G2 | 41 (82%) | 35 (70%) | |
G3 | 4 (8%) | 9 (18%) | |
Axillary lymph node metastasis | |||
Negative | 24 (48%) | 28 (56%) | 0.462b |
Positive | 26 (52%) | 22 (44%) | |
Lymphovascular invasion | |||
Negative | 31 (62%) | 38 (76%) | 0.171b |
Positive | 19 (38%) | 12 (24%) | |
ER | |||
Negative | 20 (40%) | 22 (44%) | 0.668b |
Positive | 25 (50%) | 24 (48%) | |
NA | 5 (10%) | 4 (8%) | |
PR | |||
Negative | 19 (38%) | 16 (32%) | 0.913b |
Positive | 26 (52%) | 30 (60%) | |
NA | 5 (10%) | 4 (8%) | |
Her-2 | |||
Negative | 31 (62%) | 27 (54%) | 0.915b |
Positive | 14 (28%) | 19 (38%) | |
NA | 5 (10%) | 4 (8%) | |