Table 4 Clinical and pathological characterization of familial BC patients with prevalence of TP53 rs1042522 genotypes carrying the high-risk allele [Pro/Arg (CG) and Arg/Arg (GG)]

Tumor size [cm]

Mean ± SD

2.3 ± 1.7

2.6 ± 1.2

0.153^a

Tumor grade

G1

3 (%)

2 (%)

0.674^b

G2

19 (%)

22 (%)

G3

3 (%)

1 (%)

Axillary lymph node metastasis

Negative

11 (%)

13 (%)

0.576^b

Positive

14 (%)

12 (%)

Lymphovascular invasion

Negative

15 (%)

16 (%)

0.347^b

Positive

10 (%)

9 (%)

ER

Negative

8 (%)

12 (%)

0.539^b

Positive

15 (%)

10 (%)

NA

2 (%)

3 (%)

PR

Negative

9 (%)

10 (%)

0.196^b

Positive

14 (%)

12 (%)

NA

2 (%)

3 (%)

Her-2

Negative

9 (%)

14 (%)

0.139^b

Positive

14 (%)

8 (%)

NA

2 (%)

3 (%)