Table 4 Overall knowledge of inheritance patterns (Domain 3)
From: Knowledge of genetics of hearing and genetic counseling among practicing audiologists
Inheritance pattern | Correct response N (%) | Incorrect response N (%) |
|---|---|---|
(1) Genetic diseases can be categorised into? (Single-gene, multifactorial, and chromosomal) | 121 (91%) | 12 (9%) |
(2) For a patient with hereditary hearing loss, how many generations in a pedigree chart are required for finding the pattern of inheritance? (Three generations) | 86 (64.7%) | 47 (35.3%) |
(3) How many copies of a gene are mutated to express the phenotype of a condition in autosomal dominant disorder? (One copy) | 66 (49.6%) | 67 (50.4%) |
(4) The below pedigree chart shows which pattern/mode of inheritance? (Autosomal recessive inheritance) | 76 (57.1%) | 58 (42.9%) |
(5) Mitochondrial associated mutation is? (Maternal inheritance) | 51 (38.3%) | 82 (61.7%) |
(6) The below pedigree chart shows which pattern/mode of inheritance? (X-Linked dominant inheritance) | 56 (42.1%) | 77 (57.9%) |
(7) Usher’s syndrome is a type of? (Autosomal recessive inheritance) | 79 (59.4%) | 54 (40.6%) |
(8) A newborn child has a bilateral profound sensorineural hearing impairment. This type of hearing impairment can be inherited in one of the following patterns? (Recessive or Dominant- Both) | 88 (66.2%) | 45 (33.8%) |