Table 1 Genotype and allele frequencies of HER2 and PHB gene polymorphisms in infertile and fertile men
From: Investigation of HER2 I655V and PHB 3′UTR C > T polymorphisms in azoospermic infertile males
Gene (polymorphism) | Infertile men n = 133 (%) | Fertile men (n = 100) | p | OR (95% Cl) |
|---|---|---|---|---|
HER2 I655V (A > G) | HWE p = 0.128 | HWE p = 0.676 | ||
Genotypes | ||||
AA | 102 (76.6) | 77 (77.0) | 0.503 | |
AG | 31 (23.3) | 22 (22.0) | ||
GG | 0 | 1 (1.0) | ||
AA: AG + GG | 102:31 | 77:22 | 0.956 | 1.02 (0.55–1.9) |
Allel | ||||
A | 235 (88.3) | 176 (88.0) | 0.909 | 0.97 (0.55–1.72) |
G | 31 (11.6) | 24 (12.0) | ||
PHB 3'UTR C > T | HWE p = 0.191 | HWE p = 0.691 | ||
Genotypes | ||||
CC | 90 (67.6) | 65 (65.0) | 0.544 | |
CT | 36 (27.1) | 32 (32.0) | ||
TT | 7 (5.3) | 3 (3.0) | ||
CC: CT + TT | 90: 43 | 65: 35 | 0.669 | 0.89 (0.51–1.54) |
Allel | ||||
C | 216 (81.2) | 162 (81.0) | 0.956 | 0.99 (0.62–1.58) |
T | 50 (18.7) | 38 (19.0) |