Table 1 Example of few cancers where LHPP plays essential role.
Serial no. | Cancer name | Pathway by which LHPP exerts tumor suppressor effect |
|---|---|---|
1 | Oral squamous cancer | PI3K/AKT signaling pathway [11] |
2 | Hepatocellular carcinoma | PI3K/AKT signaling pathway [12] |
3 | Breast carcinoma | PI3K/AKT signaling pathway [13] |
4 | Bladder carcinoma | AKT/p65 signaling pathway [14] |
5 | Papillary thyroid carcinoma | AKT/AMPK/mTOR signaling pathway [15] |
6 | Pancreatic carcinoma | PTEN/AKT signaling pathway [16] |
7 | Cervical cancer | PI3K/AKT signaling pathway [13] |
8 | Glioblastoma | Akt and Wnt/β-catenin signaling [3] |
9 | Gastric cancer | By influencing the metabolism of GC by altering the acetylation level [4] |
10 | Colorectal cancer | TGF- β Pathway [17] |