An exploratory pharmacogenetic screening of SLC22A6, SLC22A8, ABCC4 and ABCC10 genes in a cohort of Ghanaian HBV patients

Egyptian Journal of Medical Human Genetics

Table 5 SNP genotypes among patients and eGFR

	Total number in category	Stage 1/normal (> 90 mL/min/1.73 m²)	Stage 2 (> 60–89.99 mL/min/1.73 m²)	Stage 3a (> 45–59.99 mL/min/1.73 m²)	Stage 3b (> 30–44.99 mL/min/1.73 m²)	Stage 4 (15–29.99 mL/min/1.73 m²)	Stage 5 (< 15 mL/min/1.73 m²)	P value
Genotype
ABCC10 rs831311
CC	105	32	51	14	6	1	1	0.565
TC	49	15	20	7	4	2	1
TT	6	3	1	2	0	0	0
Total	160	50	72	23	10	3	2
SLC22A6 rs12293966
AA	76	18	34	14	5	3	2	0.104
GA	64	23	33	6	2	0	0
GG	20	9	5	3	3	0	0
Total	160	50	72	23
SLC22A6 rs4149170
CC	63	15	31	11	3	2	1	0.904
TC	40	17	14	5	4	0	0
TT	57	18	27	7	3	1	1
Total
ABCC10 rs700008
GG	132	39	60	21	8	2	0	0.715
GA
AA	28	11	12	2	2	1	2
Total
ABCC4 rs9282570
TT	145	44	66	21	10	2	2	0.772
TC	13	6	4	2	0	1	0
CC	2	0	2	0	0	0	0
Total
SLC22A6 rs955434
GG	132	44	58	20	8	1	1	0.153
GA	28	6	14	3	2	2	1
AA	0	0	0	0	0	0	0
Total
SLC22A8 rs11568487
GG	149	47	66	22	9	3	2	0.961
GT	11	3	6	1	1	0	0
TT	0	0	0	0	0	0	0
Total
SLC22A6 rs6591722
TT	140	45	62	20	8	3	2	0.900
AT	20	5	10	3	2	0	0
AA	0	0	0	0	0	0	0
Total