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Egyptian Journal of Medical Human Genetics

Table 2 Association of apoB with cardiometabolic abnormalities

From: Association of angiotensin-converting enzyme I/D polymorphism and apolipoprotein B with cardiometabolic abnormalities among young adults: a pilot study from Delhi

Variable

Status

ApoB quartiles (in mg/dl)

p value

β (SE)

p value

1st (< 72.0)

2nd (72.0–83.5)

3rd (83.5–98.8)

4th (≥ 98.8)

BP

Normotensive

35 (79.55)

41(89.13)

33 (73.33)

25 (59.52)

0.01*

0.088 (0.056)$

0.12

 

Hypertensive

9 (20.45)

5 (10.87)

12 (26.67)

17 (39.5)

 

0.106 (0.037)&

< 0.01*

BMI

Non-obese

38 (86.4)

40 (87.0)

32 (71.1)

24 (40.48)

< 0.01*

0.091 (0.016)

< 0.01*

 

Overweight/Obese

6 (13.6)

6 (13.0)

13 (28.9)

18 (42.9)

   

WC

High

5 (11.4)

8 (17.4)

13 (28.9)

17 (40.5)

< 0.01*

0.265 (0.049)

< 0.01*

 

Normal

39 (88.6)

38 (82.6)

32 (71.1)

25 (59.5)

   

WHR

High

10 (22.7)

17 (37.0)

23 (51.1)

21 (50.0)

0.02*

0.001 (0.000)

< 0.01*

 

Normal

34 (77.3)

29 (63.0)

22 (48.9)

21 (50.0)

   

WHtR

High

7 (15.9)

8 (17.4)

19 (42.2)

24 (57.1)

< 0.01*

0.002 (0.000)

< 0.01*

 

Normal

37 (84.1)

38 (82.8)

26 (57.8)

18 (42.9)

   

TC

Abnormal

0 (0.0)

0 (0.0)

1 (2.2)

13 (31.0)

< 0.01*

1.394 (0.060)

< 0.01*

 

Normal

44 (100.0)

46 (100.0)

44 (97.8)

29 (69.0)

   

TG

Abnormal

0 (0.0)

8 (17.4)

9 (20.0)

25 (59.5)

< 0.01*

1.717 (0.156)

< 0.01*

 

Normal

44 (100.0)

38 (82.6)

36 (80.0)

17 (40.0)

   

HDL

Abnormal

7 (15.9)

11 (23.9)

11 (24.4)

2 (4.8)

0.05*

0.023 (0.043)

0.60

 

Normal

37 (84.1)

35 (76.1)

34 (75.6)

40 (95.2)

   

LDL

Abnormal

0 (0.0)

0 (0.0)

0 (0.0)

11 (26.2)

< 0.01*

1.236 (0.020)

< 0.01*

 

Normal

44(100.0)

46 (100.0)

45 (100.0)

31 (73.8)

   

FBG

Abnormal

2 (4.5)

6 (13.0)

7 (15.6)

4 (9.5)

0.36

0.055 (0.045)

0.22

 

Normal

42 (95.5)

40 (87.0)

38 (84.4)

38 (90.5)

   
  1. BP, blood pressure; BMI, body mass index; WC, waist circumference; WHR, waist hip ratio; WHtR, waist height ratio; TC, total cholesterol; TG, triglyceride; HDL, high-density lipoprotein; LDL, low-density lipoprotein; FBG, fasting blood glucose; apoB, apolipoprotein B; β, beta coefficient; SE, standard error
  2. $Systolic blood pressure
  3. &Diastolic blood pressure
  4. *Significance at p value ≤ 0.05
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