Table 3 The frequency of the alleles and genotypes for SNPs studied in cases and the controls
Gene | SNP | Genotype | Cases, n (%) | Controls, n (%) | OR* | 95% CI* | P* |
|---|---|---|---|---|---|---|---|
EGFR | rs712829 | GG | 30 (30) | 20 (20) | 1.00 (Reference) | 1.00 | |
GT | 55 (55) | 25 (25) | 0/682 | 0/299–1/555 | 0/362 | ||
TT | 15 (15) | 55 (55) | 5/500 | 2/239–13/510 | 0/000 | ||
Alleles | |||||||
G | 115 (57/5) | 62 (31) | 1.00 (Reference) | 1.00 | |||
T | 85 (42/5) | 138 (69) | 2/976 | 1/557–5/691 | 0.001 | ||
Exo1 | rs1047840 | AA | 20 (20) | 5 (5) | 1.00 | 1.00 | |
GA | 22 (22) | 17 (17) | 3/111 | 0/848–11/408 | 0/087 | ||
GG | 58 (58) | 78 (78) | 5/391 | 1/690–17/200 | 0/004 | ||
Alleles | |||||||
A | 62 (31) | 27 (13/5) | 1.00 (Reference) | 1.00 | |||
G | 138 (69) | 173 (86/5) | 2/851 | 1/291–6/300 | 0.010 | ||
LEP | rs7799039 | GG | 16 (16) | 13 (31) | 1.00 (Reference) | 1.00 | |
GA | 53 (53) | 50 (53) | 0/808 | 0/318–2/050 | 0/653 | ||
AA | 31 (31) | 37 (16) | 0/641 | 0/240–1/709 | 0/374 | ||
Alleles | |||||||
G | 75 (37/5) | 85 (42/5) | 1.00 (Reference) | 1.00 | |||
A | 125 (62/5) | 115 (57/5) | 0/812 | 0/431–1/530 | 0.519 |