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Egyptian Journal of Medical Human Genetics

Table 6 Analysis of protein stability the rs1047840 of Exo1 gene by MUpro

From: Investigating the importance of EGFR (− 216G/T), Exo1 (K589E) and LEP (− 2548G/A) gene polymorphisms with risk of lung cancer as potential diagnostic biomarker in Iranian population

Gene

SNP ID

Amino acid change

I-Mutant 3.0

MUpro

DDG Value

Stability

RI

DDG Value

Stability

CS

EXO1

rs1047840

E589K

− 0.71

Decrease

5

− 1.24842

Decrease

− 0.407

  1. RI Reliability Index, CS Confidence Score
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