Skip to main content

Table 8 Analysis of rs712829 and rs7799039 by SNP Function Prediction

From: Investigating the importance of EGFR (− 216G/T), Exo1 (K589E) and LEP (− 2548G/A) gene polymorphisms with risk of lung cancer as potential diagnostic biomarker in Iranian population

dbSNP ID

Chromosome (Gene)

Position

Allele

TFBS

Splicing(site)

Splicing (ESE or ESS)

Conservation

rs712829

7 (EGFR)

55,054,249

G/T

Yes

Yes

0.001

rs7799039

7 (LEP)

127,666,019

A/G

Yes

0.000

  1. TFBS: Transcription factor-binding site, ESE: Exonic splicing enhancer, ESS: Exonic splicing silencer