From: Association of ADAM33 gene with COPD pathophysiology: a case–control study
Characteristics | COPD n = 50 | Controls n = 50 | p value |
---|---|---|---|
Age years (mean ± SD) | 56.71 + 11.87 | 51.08 + 8.03 | 0.01* |
Gender n (%) | Males = 41 Females = 9 | Males = 24 Females = 26 | < 0.001** |
BMI KG/M2 (mean ± SD) | 32.26 ± 9.07 | 37.35 ± 7.15 | 0.02* |
Smoker/non-smoker | 50/0 100/0.0% | 10/40 20/80% | < 0.001** |
Pack years | 23.5 ± 1.58 | 4.80 ± 9.78 | < 0.001** |
Presence of chronic cough | 50 (100%) | 46(92%) | 0.04* |
Diabetes mellitus | 11 | 15 | 0.19 |
Breathlessness | 48 | 39 | 0.01* |
Osteoporosis | 0 | 8 | 0.01* |
Cardiac disease | 6 | 3 | 0.40 |
Sputum production | 45 | 28 | < 0.001** |
Psychological disorders | 3 | 4 | 0.64 |
Hypertension | 12 | 4 | 0.02* |
Frequency of C allele | 7 (14.0) % | 16 (32.0) % | 0.03* |
Frequency of G allele | 50 (100) % | 36 (72.0) % | < 0.001** |