Table 1 Descriptive demographic, clinical, and laboratory data of the studied patients
Parameter | All patients n = 60 | Group I n = 30 | Group II n = 30 | |
|---|---|---|---|---|
Age (years) | Mean ± SD | 54.93 ± 9.48 | 56.43 ± 8.60 | 53.43 ± 10.22 |
Gender n (%) | Male | 36 (60.0) | 15 (50) | 21 (70) |
Female | 24 (40.0) | 15 (50) | 9 (30) | |
Bone aches n (%) | Yes | 38 (63.3) | 28 (93.3) | 10 (33.3) |
No | 22 (36.7) | 2 (6.7) | 20 (66.7) | |
Anemic symptoms n (%) | Yes | 39 (65) | 28 (93.3) | 11 (36.7) |
No | 21(35.0) | 2 (6.7) | 19 (63.3) | |
Renal impairment n (%) | Yes | 14 (23.3) | 10 (33.3) | 4 (13.3) |
No | 46 (76.7) | 20 (66.7) | 26 (86.7) | |
International staging system n (%) | I | 31 (51.7) | 5 (16.7) | 26 (86.7) |
II | 12 (20.0) | 8 (26.6) | 4 (13.3) | |
III | 17 (28.3) | 17 (56.7) | 0 | |
TLC (X103/μl) | Mean ± SD | 6.31 ± 2.57 | 6.97 ± 3.03 | 5.64 ± 1.82 |
Hb (g/dl) | Mean ± SD | 10.82 ± 2.12 | 9.47 ± 1.63 | 12.16 ± 1.67 |
PLT (X103/μl) | Mean ± SD | 244.97 ± 108.16 | 228.03 ± 109.70 | 261.90 ± 105.71 |
Serum albumin (g/dl) | Mean ± SD | 3.35 ± 0.59 | 2.91 ± 0.40 | 3.79 ± 0.39 |
M band (g/dl) n (%) | Absent | 12 (20) | 0 (0) | 12 (40) |
Present | 48 (80.0) | 30 (100) | 18 (60) | |
S.creatinine (mg/dl) | Median (IQR) | 1 (0.8–1.5) | 2.95 (0.95–6.3) | 0.9 (0.8–1.1) |
β2 microglobulin (mg/L) | Median (IQR) | 3.2 (2.5–5.7) | 5.7 (3.9–10.5) | 2.5 (2.1–2.9) |
BMPCs (%) | Median (IQR) | 7.5 (3–55) | 55 (30–80) | 3 (1.5–4) |
FAM72D | Median (IQR) | 0.89 (0.43–2.014) | 1.905 (0.671–4.563) | 0.747 (0.260–1.101) |