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Table 4 Comparison between different patients as regards the levels of FAM72D expression

From: FAM72D in plasma cell myeloma: a friend or enemy

Parameter

 

FAM72D ≥ 1

n = 28

FAM72D < 1

n = 32

p-value

Significance

Age (years)

Mean ± SD

54.11 ± 9.45

55.66 ± 9.61

0.533

NS#

Gender

n (%)

Male

16 (57.1)

20 (62.5)

0.673

NS*

 

Female

12 (42.9)

12 (37.5)

  

Bone aches

n (%)

Yes

22 (78.6)

16 (50.0)

0.022

S*

 

No

6 (21.4)

16 (50.0)

  

Anemic symptoms

n (%)

Yes

22 (78.6)

17 (53.1)

0.039

S*

 

No

6 (21.4)

15 (46.9)

  

Renal impairment

n (%)

Yes

8 (28.6)

6 (18.8)

0.370

NS*

 

No

20 (71.4)

26 (81.3)

  

International staging system

n (%)

I

12 (42.9)

19 (59.4)

0.209

NS*

II

5 (17.9)

7 (21.9)

III

11 (39.3)

6 (18.8)

TLC

(X103/μl)

Mean ± SD

6.16 ± 3.14

6.43 ± 1.97

0.695

NS#

Hb

(g/dl)

Mean ± SD

10.24 ± 2.09

11.32 ± 2.05

0.047

S#

PLT

(X103/μl)

Mean ± SD

242.04 ± 112.53

247.53 ± 105.94

0.846

NS#

Serum albumin

(g/dl)

Mean ± SD

3.11 ± 0.53

3.56 ± 0.57

0.002

HS#

M band (g/dl)

n (%)

Absent

25 (89.3)

23 (71.9)

0.093

NS*

 

Present

3 (10.7)

9 (28.1)

  

S.creatinine

(mg/dl)

Median (IQR)

1.05 (0.8–5)

0.9 (0.8–1.2)

0.340

NS**

β2 microglobulin

(mg/L)

Median (IQR)

4 (2.7–8.25)

2.9 (2.3–4.55)

0.076

NS**

BMPCs (%)

Median (IQR)

57.5 (4.75–82.5)

3 (1.75–21)

0.000

HS**

  1. Bold values indicate statistically significant
  2. TLC = total leucocyte count, SD = Standard deviation, n = number, Hb = hemoglobin, PLT = platelet, M band = monoclonal band, IQR = Interquartile range, BMPCs = bone marrow plasma cells
  3. HS = highly significant (p value < 0.01), S = significant (p value < 0.05), NS = non- significant (p-value > 0.05)
  4. *Chi-square test
  5. # Independent t-test **Mann–Whitney test