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Table 4 Project HOPE software tool modeling results of GABRA1, GABRB1, GABRB3

From: In silico analysis of missense SNPs in GABRA1, GABRB1, and GABRB3 genes associated with some diseases in neurodevelopmental disorders

SNP number

Modeling

Explanation

rs121434579

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Conversion of Alanine to Aspartic acid at position 322 as a result of the rs121434579 polymorphism

rs139163545

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Conversion of Arginine to Tryptophan at position 147 as a result of the rs139163545 polymorphism

rs267600530

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Conversion of Serine to Phenylalanine at position 303 as a result of the rs267600530 polymorphism

rs74608570

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Conversion of Aspartic acid to Glycine at position 450 as a result of the rs74608570 polymorphism

rs75612351

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Conversion of Leucine to Proline at position 458 as a result of the rs75612351 polymorphism

rs78815529

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Conversion of Tryptophan to Cysteine at position 469 as a result of the rs78815529 polymorphism

rs78196007

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Conversion of Threonine to Isoleucine at position 85 as a result of the rs78196007 polymorphism

rs78196007

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Conversion of Threonine to Isoleucine at position 156 as a result of the rs78196007 polymorphism

rs17850679

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Conversion of Leucine to Glutamine at position 173 as a result of the rs17850679 polymorphism

rs72708067

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Conversion of Methionine to Valine at position 80 as a result of the rs72708067 polymorphism

rs111596597

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Conversion of Isoleucine to Threonine at position 213 as a result of the rs111596597  polymorphism

rs149963014

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Conversion of Tyrosine to Cysteine at position 324 as a result of the rs149963014

polymorphism