Table 8 Comparison of induced apoptosis with necrosis by plant extract in 24-, 48- and 72-h treatment on MCF-7 cell line
From: Effect of Dioscorea extract on Bax and Bcl-2 gene expression in MCF-7 and HFF cell lines
IC50 (24 h) | IC50 (48 h) | IC50 (72 h) | |
|---|---|---|---|
Apoptotic cells | 6.63 ± 0.34 | 14.28 ± 0.29 | 20.49 ± 0.39 |
Necrotic cells | 0.477 ± 0.31 | 1.12 ± 0.36 | 1.94 ± 0.35 |
p value | p value < 0.001 | p value < 0.001 | p value < 0.001 |