Table 9 Evaluation of apoptosis induced by plant extract in 24-, 48- and 72-h treatment on MCF-7 and HFF cell lines
From: Effect of Dioscorea extract on Bax and Bcl-2 gene expression in MCF-7 and HFF cell lines
Control | 24 (h) | 48 (h) | 72 (h) | |
|---|---|---|---|---|
Early Apoptosis | 0.074 ± 0.18 | 1.29 ± 0.23 p value = 0.089 | 4.51 ± 0.32 p value = 0.12 | 11.2 ± 0.38 p value < 0.001 |
Delayed Apoptosis | 0.064 ± 0.23 | 5.34 ± 0.27 p value < 0.001 | 9.77 ± 0.35 p value < 0.001 | 9.29 ± 0.31 p value < 0.001 |
Necrosis | 0.032 ± 0.25 | 0.477 ± 0.29 p value = 0.067 | 1.12 ± 0.26 p value = 0.087 | 1.94 ± 0.27 p value = 0.095 |