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Egyptian Journal of Medical Human Genetics
Fig. 3 | Egyptian Journal of Medical Human Genetics

Fig. 3

From: B-lymphocyte-activating factor is a potential biomarker associated with susceptibility to Graves’ disease in Iraqi women

Fig. 3

Column-bar plots of serum B-lymphocyte-activating factor (BAFF) levels stratified by genotypes of BAFF single nucleotide polymorphisms (Plot A: rs9514827; Plot B: rs9514828) in Graves' disease patients plus controls. Columns indicates median, while bars represent interquartile range (IQR). Significance was assessed using Mann–Whitney U test (*p < 0.05; **p < 0.01; ns: not significant). The CC genotype of rs9514827 tended to show higher BAFF levels compared to the TT genotype but the differences were not significant (p = 0.16). For rs9514828, the TT genotype was associated with significantly increased serum levels of BAFF compared to the CC and CT genotypes (1516 [IQR: 884–1943] vs. 799 [IQR: 619–1517] and 871 [IQR: 649–1454] pg/mL; p = 0.005 and 0.02, respectively), while there was no significant difference between CC and CT genotypes (p = 0.64)

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