Table 1 Lipinski’s drug-likeness screening of the bioactive compounds and the control medication
S/N | Plants | Bioactive compounds | Chemical formulae | Molecular weight | LogP | Number of HB acceptor | Number of HB donor | No. of violation |
|---|---|---|---|---|---|---|---|---|
1 | Adansonia digitata L | Catechin | C15H14O6 | 290.27 | 0.36 | 6 | 5 | 0 |
| Â | Â | Epicatechin | C15H14O6 | 290.27 | 0.36 | 6 | 5 | 0 |
| Â | Â | Vitexin | C21H20O10 | 432.38 | 0.21 | 10 | 7 | 1 |
| Â | Â | Quercetin | C15H10O7 | 302.24 | 1.54 | 7 | 5 | 0 |
| Â | Â | Kaempferol | C15H10O6 | 286.24 | 1.90 | 6 | 4 | 0 |
|  |  | Rutin | C27H30O16 | 610.52 | − 0.33 | 16 | 10 | 3 |
2 | Aframomum melegueta K. Schum | n-Hexadecanoic acid | C16H32O2 | 256.42 | 7.17 | 2 | 1 | 1 |
| Â | Â | Corymbolone | C15H24O2 | 236.35 | 2.98 | 2 | 1 | 0 |
| Â | Â | Gamma-Sitosterol | C29H50O | 414.71 | 9.34 | 1 | 1 | 1 |
| Â | Â | Myrtenyl acetate | C12H18O2 | 194.27 | 3.79 | 2 | 0 | 0 |
| Â | Â | Gamma-Muurolene | C15H24 | 204.35 | 4.31 | 0 | 0 | 1 |
| Â | Â | Isonicotinic acid | C6H5NO2 | 123.11 | 0.32 | 3 | 1 | 0 |
3 | Ageratum conyzoides (L.) L | Azulene | C10H8 | 128.17 | 3.2 | 0 | 0 | 0 |
|  |  | Norfenefrine | C8H11NO2 | 153.18 | − 0.82 | 3 | 3 | 0 |
| Â | Â | Kaur-16-ene | C20H32 | 272.47 | 6.91 | 0 | 0 | 1 |
| Â | Â | 2-Acetylcyclopentanone | C7H10O2 | 126.15 | 0.35 | 2 | 0 | 0 |
| Â | Â | Alpha-Calacorene | C15H20 | 200.32 | 4.41 | 0 | 0 | 1 |
| Â | Â | Longipinocarveol, trans | C15H24O | 220.35 | 3.85 | 1 | 1 | 0 |
4 | Boswellia dalzielii Hutch | Lavandulol | C10H18O | 154.25 | 3.02 | 1 | 1 | 0 |
| Â | Â | Cyperene | C15H24 | 204.35 | 4.32 | 0 | 0 | 1 |
| Â | Â | Aromadendrene | C15H24 | 204.35 | 4.71 | 0 | 0 | 1 |
| Â | Â | Viridiflorol | C15H26O | 222.37 | 3.74 | 1 | 1 | 0 |
| Â | Â | Cis-Chrysanthemol | C10H18O | 154.25 | 2.52 | 1 | 1 | 0 |
| Â | Â | Beta-Phellandrene | C10H16 | 136.23 | 3.44 | 0 | 0 | 0 |
| Â | Control medication | Remdesivir | C27H35N6O8P | 602.58 | 1.91 | 12 | 4 | 2 |