Outcome | Control versus thalassemia intermedia | Control versus thalassemia major | Thalassemia intermedia versus thalassemia major | |||
---|---|---|---|---|---|---|
MD (95% CI) | p value | MD (95% CI) | p value | MD (95% CI) | p value | |
Block design | 5.28 (4.94–5.65) | 0.001 | 6.35 (6.00–6.70) | 0.001 | 1.07 (0.69–1.42) | 0.001 |
Similarities | 5.40 (5.04–5.79) | 0.001 | 6.57 (6.20–6.94) | 0.001 | 1.17 (0.76–1.54) | 0.001 |
Digit span | 5.34 (4.81–5.80) | 0.001 | 6.93 (6.45–7.42) | 0.001 | 1.60 (1.12–2.14) | 0.001 |
Picture concepts | 4.77 (4.39–5.19) | 0.001 | 6.56 (6.17–6.95) | 0.001 | 1.79 (1.36–2.18) | 0.001 |
Coding | 6.01 (5.59–6.36) | 0.001 | 7.46 (7.07–7.84) | 0.001 | 1.44 (1.08–1.88) | 0.001 |
Vocabulary | 5.06 (4.66–5.48) | 0.001 | 6.43 (6.02–6.83) | 0.001 | 1.37 (0.93–1.78) | 0.001 |
Letter–number sequencing | 4.64 (4.25–5.03) | 0.001 | 5.83 (5.45–6.22) | 0.001 | 1.19 (0.78–1.59) | 0.001 |
Matrix reasoning | 5.40 (4.97–5.84) | 0.001 | 6.83 (6.40–7.25) | 0.001 | 1.43 (0.97–1.88) | 0.001 |
Comprehension | 5.85 (5.45–6.28) | 0.001 | 7.08 (6.68–7.49) | 0.001 | 1.23 (0.79–1.65) | 0.001 |
Symbol search | 5.35 (5.01–5.70) | 0.001 | 6.39 (6.06–6.73) | 0.001 | 1.04 (0.68–1.39) | 0.001 |
Picture completion | 5.12 (4.63–5.60) | 0.001 | 6.11 (5.63–6.58) | 0.001 | 0.98 (0.49–1.49) | 0.001 |
Cancellation | 4.86 (4.37–5.32) | 0.001 | 5.57 (5.10–6.03) | 0.001 | 0.71 (0.23–1.21) | 0.001 |
Information | 5.29 (4.87–5.71) | 0.001 | 6.95 (6.53–7.36) | 0.001 | 1.66 (1.22–2.09) | 0.001 |
Arithmetic | 5.17 (4.72–5.64) | 0.001 | 6.30 (5.85–6.76) | 0.001 | 1.14 (0.65–1.60) | 0.001 |
Word reasoning | 4.25 (3.81–4.69) | 0.001 | 5.50 (5.07–5.93) | 0.001 | 1.26 (0.79–1.70) | 0.001 |
Verbal Comprehension Index | 15.78 (14.41–17.24) | 0.001 | 19.55 (18.17–20.94) | 0.001 | 3.77 (2.26–5.20) | 0.001 |
Perceptual Reasoning Index | 15.45 (14.63–16.34) | 0.001 | 19.74 (18.90–20.58) | 0.001 | 4.29 (3.37–5.14) | 0.001 |
Working Memory Index | 9.98 (9.30–10.59) | 0.001 | 12.77 (12.14–13.40) | 0.001 | 2.79 (2.15–3.49) | 0.001 |
Processing Speed Index | 11.38 (10.80–11.91) | 0.001 | 13.85 (13.30–14.39) | 0.001 | 2.46 (1.92–3.07) | 0.001 |
Full scale score index | 53.10 (50.89–55.33) | 0.001 | 66.43 (64.26–68.60) | 0.001 | 13.33 (11.02–15.62) | 0.001 |