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Table 3 Clinicopathological characteristics of BC cases

From: STAT3 gene polymorphisms and susceptibility to breast cancer in the Moroccan population

Clinicopathological characteristics

Cases n (%) N = 200

Controls n (%) N = 200

P value

Age (mean ± SD)

48.20 ± 10.52

48.21 ± 10.46

1

Menopause

 Pre

130 (65)

136 (68)

0.53

 Post

70 (35)

64 (32)

 

Tumor histology

 IDC

149 (84.66)

–

–

 ILC

16 (9.09)

  

 Medulary

1 (0.57)

  

 Other

10 (5.68)

  

SBR grading

 I

9 (5.14)

–

–

 II

102 (58.29)

  

 III

64 (36.57)

  

Estrogen receptor (ER)

 Pos

143 (78.57)

–

–

 Neg

39 (21.43)

  

Progesterone receptor (PR)

 Pos

110 (68.32)

–

–

 Neg

51 (31.68)

  

Human epidermal growth factor 2 (HER2) receptor

 Pos

46 (29.11)

–

–

 Neg

112 (70.89)

  

Immuno-histochemical (IHC) subtypes

 Luminal A

85 (54.49)

–

–

 Luminal B

35 (22.44)

  

 Triple neg

26 (16.66)

  

 HER2/neu

10 (6.41)

  
  1. IDC invasive ductal carcinoma, ILC invasive lobular carcinoma, Neg negative, Pos positive, Luminal A ER+ and/or PR+ ER−/PR+ with HER2−, Luminal B ER+ and/or PR+ ER−/PR+ with HER2+, Triple-negative ER−, PR−, HER2−, HER2/neu ER−, PR− with HER2+