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Egyptian Journal of Medical Human Genetics

Table 5 Relationships of the studied miRNAs with different parameters of the MS patients

From: The significance of miRNA-191-5P and miRNA-24-3P as novel biomarkers for multiple sclerosis: a case–control study

Clinical Parameters of MS (n = 80)

Median values of miRNAs

p value

Sex

Male

Female

     

miR-191

0.92 (0.01–1601.27)

1.05 (0.01–389.37)

    

 0.79

miR-24

2.85 (0–137.66)

2.34 (0–680.29)

    

 0.929

Initial presentation

Motor

Sensory

Visual

Brainstem

Ataxia

Bladder/others

 

miR-191

0.98

0.71

2.02

18.54

4.52

0.95

0.113

miR-24

0.92

2.43

4.58

10.27

50.07

0.99

0.13

Number of lesions

1–3

4–9

>  = 10

    

miR-191

0.92 (0.01–1601.27)

1.01 (0.01–47.50)

1.01 (0.01–350.92)

   

 0.702

miR-24

2.38 (0–137.66)

0.99 (0.02–114.56)

1.75 (0–680.29)

   

 0.991

MRI Enhancement

Without T1 enhancement

With T1 enhancement

     

miR-191

0.99 (0.01–1601.27)

3.73 (0.18–47.50)

    

 0.225

miR-24

2.38 (0–680.29)

3.71 (0.08–114.56)

    

 0.817

  1. p value significant: p ≤ 0.05.
  2. p value highly significant: p ≤ 0.001.
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