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Table 1 Distribution of MTHFR polymorphism in control and case groups

From: MTHFR (C677T) polymorphism and its association with cytogenetic and clinical profile in individuals with primary amenorrhea

MTHFR polymorphism

Control (n = 45)

Cases (n = 45)

Chi-square Value

p-value

CC (n = 60)

38 (84.4%)

22 (48.9%)

Reference

Reference

CT (n = 17)

6 (13.3%)

11 (24.4%)

4.253

P = 0.039*

TT (n = 13)

1 (2.2%)

12 (26.7%)

13.294

P = 0.000266***

C

82 (91%)

55 (61.1%)

Reference

Reference

T

8 (8.9%)

35 (38.9%)

22.275

P = 0.000002***

  1. *p<0.05, ***p<0.001