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Table 3 Association of MTHFR polymorphism with hormone profile of case group females

From: MTHFR (C677T) polymorphism and its association with cytogenetic and clinical profile in individuals with primary amenorrhea

Hormones

CC (n = 22)

CT (n = 11)

TT (n = 12)

p-value

FSH (2.5-10.2 mIU/ml)

32.6±44.1

25.3±23

61.6±61.1

NS

LH (2.39-6.6 mIU/ml)

14.3±16.7

18.1±19.1

18.1±16.9

NS

TSH (0.4-4.2 µIU/mL)

2.8±1.6

2.5±2.3

2.1±0.6

NS

Prolactin (4-30 ng/mL)

122.3±427.7

15.8±14.2

45.7±119.1

NS

Estrogen (21-251 pg/ml)

50±66.1

53.2±49.7

51.1±42.4

NS

Progesterone (0.1-25 ng/mL)

3.7±2.7

2.1±2.4

1.3±2.4

0.032*

Testosterone (14-76 ng/dL)

16.5±12.1

16±7.1

19.1±11.1

NS

  1. A one-way ANOVA test for analysis of variance was conducted: *p<0.05, and NS Non-significant association was observed within the groups.
  2. Values were represented as mean±SD