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Table 2 Patient characteristics and their clinical data

From: Association between genetic polymorphisms and other attributing factors with lipid profiles among statin users: a cross-sectional retrospective study

Characteristics

n = 229a

Age, mean years ± SD (range)

53 ± 7.16 (29–69)

Gender, n (%)

 Female

122 (53.3)

 Male

107 (46.7)

Race, n (%)

 Malay

220 (96.1)

 Chinese

7 (3.1)

 Indian

1 (0.4)

 Others

1 (0.4)

Statin used, n (%)

 Atorvastatin (10–40 mg/day)b

147 (64.2)

 Simvastatin (10–40 mg/day)c

60 (26.2)

 Pravastatin (20 mg/day)

16 (7.0)

 Lovastatin (20 mg/day)

6 (2.6)

Diagnosed clinical manifestation, n (%)

 DM and HPT

91 (39.7)

 HPT

85 (37.1)

 HPL only

29 (12.7)

 DM and HPL

24 (10.5)

Concurrent treatment with statin, n (%)

 Anti-hypertensive drugs and diabetic medications

88 (38.4)

 Anti-hypertensive drugs only

85 (37.1)

 None

35 (15.3)

 Diabetic medications only

21 (9.2)

Antihypertensive drugs class, n (%)

 Combination of two or more anti-hypertensive drugs

99 (57.2)

 Calcium channel blockers only

33 (19.1)

 Angiotensin-converting enzyme (ACE) inhibitor only

24 (13.9)

 Angiotensin receptor blocker only

10 (5.8)

 Diuretic drugs only

4 (2.3)

 Beta-blockers only

3 (1.7)

Lipid level at the baseline, mean ± SD (mmol/L)

 TC (normal range < 5.2)

5.72 ± 1.21

 HDL-c (normal range > 1.5)

1.30 ± 0.47

 LDL-c (normal range < 2.6)

3.72 ± 1.19

 TG (normal range < 1.7)

1.65 ± 0.83

  1. DM diabetes mellitus; HDL-c high density lipoprotein; HPL hyperlipidaemia; HPT hypertension; SD standard deviation; TC total cholesterol; TG triglyceride; LDL-c low density lipoprotein
  2. aOnly 2 patients developed statin-related mild muscle pain, which disappeared with statin re-challenge
  3. bOnly 5 and 22 patients were on 30 mg/day and 40 mg/day doses, respectively
  4. cOnly three patients were on 40 mg/day simvastatin doses, while the rest received 10 to 20 mg/day