Dysregulation in growth arrest-specific 5 and metastasis-associated lung adenocarcinoma transcript 1 gene expression predicts diagnosis and renal fibrosis in systemic lupus erythematosus patients

Egyptian Journal of Medical Human Genetics

Table 1 Comparison of GAS5 and MALAT1 relative expression in all studied groups

Variable	All cases		Control	p value
Relative expression of GAS5	0.52 (0.19–1.02)		0.98 (0.88–1.06)	0.001*
Relative expression of MALAT1	3.13 (1.69–5.15)		0.91 (0.84–1.17)	< 0.001*
	Non-nephritis	Nephritis	Control
Relative expression of GAS5	0.91 (0.42–1.28)	0.24 (0.17–0.67) ^a	0.98 (0.88–1.06) ^b	< 0.001*
Relative expression of MALAT1	3.58 (1.50–5.63)	2.60 (1.89–4.20)	0.91 (0.84–1.17) ^ab	< 0.001*

Data are expressed as median (IQR). Tests used: Mann-Whitney U test and Kruskal-Wallis followed by Dunn’s post hoc for data expressed as median (IQR)
p p value
*Significance < 0.05
^aSignificance vs non-nephritis
^bSignificance vs nephritis