Guh DP, Zhang W, Bansback N, Amarsi Z, Birmingham CL, Anis AH (2009) The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis. BMC Public Health 9(1):88
Article
PubMed
PubMed Central
Google Scholar
Caballero B (2007) The global epidemic of obesity: an overview. Epidemiol Rev 29(1):1–5
Article
PubMed
Google Scholar
World Health Organization. Obesity and overweight fact sheet. https://www.who.int. Accessed 1 Apr 2020.
Tsigos C, Hainer V, Basdevant A, Finer N, Fried M, Mathus-Vliegen E et al (2008) Management of obesity in adults: European clinical practice guidelines. Obes Facts 1(2):106–116
Article
PubMed
PubMed Central
Google Scholar
Godwin SM (2006) Globalization, education and Emiratisation: a study of the United Arab Emirates. Electron J Inf Syst Dev Ctries 27(1):1–14
Article
Google Scholar
Rashidy-Pour A, Malek M, Eskandarian R, Ghorbani R (2009) Obesity in the Iranian population. Obes Rev 10(1):2–6
Article
CAS
PubMed
Google Scholar
Yazdi FT, Clee SM, Meyre D (2015) Obesity genetics in mouse and human: back and forth, and back again. PeerJ 3:e856
Article
PubMed
PubMed Central
Google Scholar
Ramachandrappa S, Farooqi IS (2011) Genetic approaches to understanding human obesity. J Clin Invest 121(6):2080–2086
Article
CAS
PubMed
PubMed Central
Google Scholar
Allison DB, Kaprio J, Korkeila M, Koskenvuo M, Neale MC, Hayakawa K (1996) The heritability of body mass index among an international sample of monozygotic twins reared apart. Int J Obes Relat Metab Disord 20(6):501–506
CAS
PubMed
Google Scholar
Acheson A, Conover JC, Fandl JP, DeChiara TM, Russell M, Thadani A et al (1995) A BDNF autocrine loop in adult sensory neurons prevents cell death. Nature 374(6521):450–453
Article
CAS
PubMed
Google Scholar
Yamada K, Nabeshima T (2003) Brain-derived neurotrophic factor/TrkB signaling in memory processes. J Pharmacol Sci 91(4):267–270
Article
CAS
PubMed
Google Scholar
Lyons WE, Mamounas LA, Ricaurte GA, Coppola V, Reid SW, Bora SH et al (1999) Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities. Proc Natl Acad Sci USA 96(26):15239–15244
Article
CAS
PubMed
Google Scholar
Rios M, Fan G, Fekete C, Kelly J, Bates B, Kuehn R et al (2001) Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity. J Mol Endocrinol 15(10):1748–1757
Article
CAS
Google Scholar
Lapchak PA, Hefti F (1992) BDNF and NGF treatment in lesioned rats: effects on cholinergic function and weight gain. Neuroreport 3(5):405–408
Article
CAS
PubMed
Google Scholar
Pelleymounter MA, Cullen MJ, Wellman CL (1995) Characteristics of BDNF-induced weight loss. Exp Neurol 131(2):229–238
Article
CAS
PubMed
Google Scholar
Thorleifsson G, Walters GB, Gudbjartsson DF, Steinthorsdottir V, Sulem P, Helgadottir A et al (2009) Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat Genet 41(1):18–24
Article
CAS
PubMed
Google Scholar
Lu B, Nagappan G, Guan X, Nathan PJ, Wren P (2013) BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases. Nat Rev Neurosci 14(6):401–416
Article
CAS
PubMed
Google Scholar
Gunstad J, Schofield P, Paul RH, Spitznagel MB, Cohen RA, Williams LM et al (2006) BDNF Val66Met polymorphism is associated with body mass index in healthy adults. Neuropsychobiology 53(3):153–156
Article
CAS
PubMed
Google Scholar
Bath KG, Lee FS (2006) Variant BDNF (Val66Met) impact on brain structure and function. Cogn Affect Behav Neurosci 6(1):79–85
Article
PubMed
Google Scholar
World Health Organization. Body mass index - BMI. https://www.euro.who.int. Accessed 13 Nov 2020.
Martínez-Ezquerro JD, Rendón-Macías ME et al (2017) Association between the brain-derived neurotrophic factor val66met polymorphism and overweight/obesity in pediatric population. Arch Med Res 48(7):599–608
Article
PubMed
CAS
Google Scholar
Wardle J, Carnell S, Haworth CM, Plomin R (2008) Evidence for a strong genetic influence on childhood adiposity despite the force of the obesogenic environment. Am J Clin Nutr 87(2):398–404
Article
CAS
PubMed
Google Scholar
Kernie SG, Liebl DJ, Parada LF (2000) BDNF regulates eating behavior and locomotor activity in mice. EMBO J 19(6):1290–1300
Article
CAS
PubMed
PubMed Central
Google Scholar
Shugart YY, Chen L, Day IN, Lewis SJ, Timpson NJ, Yuan W et al (2009) Two British women studies replicated the association between the Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) and BMI. Eur J Hum Genet 17(8):1050–1055
Article
CAS
PubMed
PubMed Central
Google Scholar
Hong KW, Lim JE, Go MJ, Shin YS, Ahn Y, Han BG et al (2012) Recapitulation of the association of the Val66Met polymorphism of BDNF gene with BMI in Koreans. Obesity 20(9):1871–1875
Article
CAS
PubMed
Google Scholar
Beckers S, Peeters A, Zegers D, Mertens I, Van Gaal L, Van Hul W (2008) Association of the BDNF Val66Met variation with obesity in women. Mol Genet Metab 95(1-2):110–112
Article
CAS
PubMed
Google Scholar
Zhang XY, Zhou DF, Wu GY, Cao LY, Tan YL, Haile CN et al (2008) BDNF levels and genotype are associated with antipsychotic-induced weight gain in patients with chronic schizophrenia. Neuropsychopharmacology 33(9):2200–2205
Article
CAS
PubMed
Google Scholar
Akkermann K, Hiio K, Villa I, Harro J (2011) Food restriction leads to binge eating dependent upon the effect of the brain-derived neurotrophic factor Val66Met polymorphism. Psychiatry Res 185(1-2):39–43
Article
CAS
PubMed
Google Scholar