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Egyptian Journal of Medical Human Genetics
Fig. 6 | Egyptian Journal of Medical Human Genetics

Fig. 6

From: In silico investigations on curcuminoids from Curcuma longa as positive regulators of the Wnt/β-catenin signaling pathway in wound healing

Fig. 6

3D representation of the best possible poses and ligand-receptor interactions between (1) curcumin I (PubChem CID: 969516), (2) curcumin II (PubChem CID: 5469424), and (3) curcumin III (PubChem CID: 5315472) and (A) casein kinase-1 (PDB Id: 2IZS) and (B) glycogen synthase kinase-3β (PDB Id: 3F88). Ligand (UNK: 900) is represented as a ball and stick and the interacting amino acid (labeled) of the receptor is represented in a stick style. The receptor is represented in ribbon style. The dotted line represents the type of interactions: green: hydrogen bond; pink: Pi-alkyl interaction; white: carbon-hydrogen bond; red: acceptor-acceptor interaction; orange: Pi-sulfur interaction

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