Momordica charantia nanoparticles promote mitochondria biogenesis in the pancreas of diabetic-induced rats: gene expression study

Egyptian Journal of Medical Human Genetics

Table 2 Effect of M. charantia nanoparticles (50 mg/kg), M. charantia crude extract (100 mg/kg), silver nitrate (10 mg/kg) and metformin (100 mg/kg) on the glucose levels of the experimental rats

Fasting blood sugar levels of the rats on different days
Treatments	Before STZ induction	72 h After STZ induction	6th day of treatment	11th day of treatment
D. control	97 ± 5.78	271 ± 1.17	261 ± 3.44^a	258 ± 7.67^a
Control	101 ± 2.4	98 ± 1.01	103 ± 6.12	89 ± 2.53
STZ + S.N (10 mg/kg)	88 ± 8.23	275 ± 5.50	195 ± 2.11^b	170 ± 5.24^b
STZ + M.C SNPs (50 mg/kg)	115 ± 1.04	277 ± 0.45	79 ± 3.46^b	65 ± 1.73^b
STZ + Metformin (100 mg/kg)	107 ± 4.27	271 ± 4.89	88 ± 6.43^b	73 ± 1.01^b
STZ + M.C (100 mg/kg)	101 ± 4.45	272 ± 1.57	108 ± 1.88^b	84 ± 1.06^b

^aStatistical difference to control (p < 0.05) while ^bstatistical difference to Diabetic control (p < 0.05). Results are expressed in mean ± SEM, n = 7