Fig. 5
From: Pathway analysis of smoking-induced changes in buccal mucosal gene expression
Upstream regulators dexamethasone and miR-8. A Chemical drug dexamethasone is predicted to be activated in smoker buccal mucosa with P value = 1.10 × 10–06 and Z score = 0.438. B miR-8 is predicted to be activated in smoker buccal mucosa with P value = 8.90 × 10–02 and Z score = 2.1. Different shapes represent the molecular class of the protein. Red and green indicate upregulation and downregulation, respectively, while blue and orange indicate inhibition and activation, respectively. A solid line indicates a direct interaction, a dashed line indicates an indirect interaction, and a dotted line indicates inferred correlation from machine-based learning. An asterisk indicates that multiple identifiers in the dataset file map to a single gene or chemical in the Global Molecular Network