In silico profiling of non-synonymous SNPs in IDS gene for early diagnosis of Hunter syndrome

Egyptian Journal of Medical Human Genetics

Table 4 List of ns-SNPs predicted as deleterious through RMSD calculation through GROMACS

S. no.	Residual change	RMSD (Å)	S. no.	Residual change	RMSD (Å)
1	D45H	0.245	22	C422Y	0.475
2	S61P	0.226	23	Q465K	0.174
3	A79G	0.327	24	Y466C	0.202
4	V83G	0.354	25	P467L	0.218
5	P86L	0.502	26	R468P	0.625
6	R88C	0.196	27	R468L	0.216
7	P97T	0.264	28	R468W	0.161
8	P120H	0.178	29	D478G	0.197
9	T130I	0.169	30	P480S	0.187
10	G134E	0.237	31	M488I	0.235
11	A205P	0.401	32	G489A	0.43
12	H229R	0.198	33	R493H	0.165
13	D252Y	0.245	34	R493C	0.242
14	R271W	0.257	35	Y497C	0.203
15	R297C	0.299	36	Y497N	0.222
16	G312D	0.449	37	R498T	0.183
17	G312S	0.292	38	T500I	0.197
18	G336W	0.165	39	W502S	0.281
19	L339P	0.46	40	V503D	0.321
20	P358T	0.282	41	E521D	0.189
21	T409M	0.268	42	D532G	0.341