Table 5 Results of trajectory analysis
From: In silico profiling of non-synonymous SNPs in IDS gene for early diagnosis of Hunter syndrome
S. no. | Tools | Protein | G134E | P358T | R468W | M488I | V503D | E521D |
|---|---|---|---|---|---|---|---|---|
1 | Psipred | Native | C | C | C | C | E | E |
Mutant | E | E | C | E | C | C | ||
2 | SRide | Native | $ | |||||
Mutant | $, # | $, # | $, # | $, # | $, #, D334 | $, # | ||
3 | Consurf | Native | 6 | 8 | 6 | 9 | 9 | 8 |
Mutant | 4 | 7 | 5 | 8 | 9 | 7 | ||
4 | Netsurf | Native | 1% | 1% | 26% | 10% | 7% | 26% |
Mutant | 2% | 2% | 18% | 10% | 18% | 18% | ||
5 | Predyflexy | Native | 1 | 0 | 1 | 2 | 0 | 1 |
Mutant | 1 | 0 | 2 | 1 | 0 | 0 | ||
6 | Missense 3D | Native | Uncharge | No change | Charge | No change | Uncharge | No change |
Mutant | Charge | Uncharge | Charge | |||||