Skip to main content
Egyptian Journal of Medical Human Genetics
Fig. 4 | Egyptian Journal of Medical Human Genetics

Fig. 4

From: Mutational analysis of phospholipase C epsilon 1 gene in Egyptian children with steroid-resistant nephrotic syndrome

Fig. 4

The WEBLOGO representation of amino acid conservation: input data as Clustal format according to multiple sequence alignment of PLCE1 between human and other organisms. 60 amino acids for PLCE1 protein(Q9P212) Homo sapiens (NP_057425.3), along with seven proteins from Gallus gallus(XP_015144344.2), Canis lupus familiaris (NP_001130037.1), Mus musculus (NP_062534.2), Rattus norvegicus (NP_446210.1), Pan troglodytes (XP_009457233.3) and Danio rerio (NP_001155125.1) and (even in PLC210 the most primitive othologe of PLCE1) Caenorhabditis elegans (AAC38963.1) a represent the logo representation of aligned positions containing R1230 (according to human sequence) While b represent the logo representation of 60 amino acids of the same organisms but in position containing the other mutant amino acid E 1393 (according to human sequence) show low conservation score than R1230

Back to article page