Table 7 Evaluation of the deleteriousness of nsSNPs by the predictSNP1.0 server based on many prediction tools
Mutation | PredictSNP | MAPP | PhD-SNP | PolyPhen-1 | PolyPhen-2 | SNAP | SIFT |
|---|---|---|---|---|---|---|---|
R1230H | Deleterious (0.606973) | Deleterious (0.409295) | Neutral (0.58231) | Deleterious (0.744912) | Deleterious (0.811429) | Neutral (0.554397) | Deleterious (0.792808) |
E1393K | Neutral (0.653073) | Neutral (0.642291) | Deleterious (0.607981) | Neutral (0.668841) | Neutral (0.711712) | Neutral (0.554397) | Deleterious (0.429699) |