Effects of ABCG2 C421A and ABCG2 G34A genetic polymorphisms on clinical outcome and response to imatinib mesylate, in Iranian chronic myeloid leukemia patients

Egyptian Journal of Medical Human Genetics

Table 4 The comparison of hematological response between patients with different genotypes

SNP	WBC (× 10³ cell/μL)			Plt (× 10⁵/μL)			Hb (g/dL)
SNP	Primary*	Secondary**	P	Primary	Secondary	P	Primary	Secondary	P
C421A /CC	135.000 ± 257.711	779.868 ± 510.220	0.710	2.30831 ± 1.39946	2.33890 ± 1.21186	0.390	12.74 ± 2.14	12.71 ± 2.08	0.746
C421A /CA	116.820 ± 131.619	109.390 ± 145.113	0.124	1.70200 ± 4.0608	1.93400 ± 2.8648	0.299	13.69 ± 2.84	13.93 ± 2.23	0.387
G34A /AG	123.875 ± 232.534	743.583 ± 462.148	0.817	2.19658 ± 1.27317	2.22916 ± 1.10475	0.476	12.93 ± 2.27	12.95 ± 2.09	0.916
G34A /GG	781.800 ± 757.694	903.108 ± 100.914	0.209	2.60041 ± 2.13952	2.41554 ± 1.65904	0.764	12.39 ± 1.90	12.37 ± 1.84	0.930