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Table 3 Genotype frequency and OR for SNP associated with disease status

From: Association between the single-nucleotide polymorphism (rs1030868) variant in matrix metallopeptidase 2 gene and the development of lymphedema

Gene (db-SNP rs#)

Functional category of SNP

Genotyping

Control (N = 187)

Cases (N = 93)

P value

AOR (95% CI)*

MMP-2 (rs1030868)

Intron

GA

172 (92%)

67 (72%)

< 0.001

Reference

GG

8 (4.3%)

10 (10.8%)

= 0.019

3.209 (1.215–6.497)

AA

7 (3.7%)

16 (17.2%)

< 0.001

5.868 (2.311–11.901)

  1. N number, % percentage, G guanine base, A adenine base
  2. Significant association (p < 0.05)
  3. *AOR = Adjusted Odds Ratio and 95% Confidence Interval of Risk of allele